Quinine Hydrochloride

Quinine hydrochloride is a salt form of quinine, a bitter compound naturally found in the bark of the cinchona tree. It is typically manufactured by chemically treating quinine extracted from the bark.

Quinine hydrochloride is primarily used as a flavoring agent to give tonic water and some other beverages a distinct bitter taste. Its bitterness is a key characteristic that manufacturers seek for these specific drink profiles.

In the U.S., quinine is approved as a food additive for flavoring purposes. The FDA has established regulations for its use in food. While quinine has a long history of medicinal use, its use in food is limited to flavoring at very low concentrations. JECFA has evaluated quinine and established an acceptable daily intake. Some individuals may experience adverse effects from quinine, such as nausea or skin reactions, particularly at higher doses than typically found in food.