Ingredient · E635

E635

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Source
Not animal-derived
Allergen
No
Role in food
E635 is used to boost savory (umami) flavors in foods. It is often found …

What it is

Disodium 5'-ribonucleotides (E635) is a flavor enhancer. It is a synthetic compound made from yeast or bacteria, or from the breakdown of RNA. It is often combined with monosodium glutamate (MSG) or other nucleotides.

Why it's used

E635 is used to boost savory (umami) flavors in foods. It is often found in instant noodles, snack foods, sauces, and processed meats. It helps make foods taste richer and more complex.

Health notes

In the US, E635 is generally recognized as safe (GRAS) by the FDA when used as intended. Regulatory bodies like JECFA and EFSA have evaluated E635 and set acceptable daily intakes. Some individuals report sensitivity to nucleotides, experiencing headaches or flushing, though scientific evidence for these reactions at typical consumption levels is mixed.

Allergen info

E635 is not derived from any of the 9 FDA major allergens. It does not contain gluten.

Products containing E635

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Last updated: September 28, 2026

Note: This site presents label data from USDA FoodData Central for general information. It is not medical advice. Check the package label; formulations change.