Ingredient

Calcium Beta-hydroxy-beta-methylbutyrate

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Source
Not animal-derived
Allergen
No
Role in food
Manufacturers add calcium HMB to foods and supplements as a source of the compound, …

What it is

Calcium beta-hydroxy-beta-methylbutyrate, also known as calcium HMB, is a compound that is naturally produced in small amounts in the human body. It is a metabolite of the amino acid leucine. For use in food, it is typically produced through chemical synthesis.

Why it's used

Manufacturers add calcium HMB to foods and supplements as a source of the compound, which is marketed for its potential benefits to muscle health and recovery. It is most often found in energy drinks, protein supplements, and specialty formulas designed for athletes or individuals seeking to support muscle mass.

Health notes

Calcium HMB is generally recognized as safe (GRAS) by the FDA for use in certain food categories. Research into its effects on muscle health and performance is ongoing, with some studies suggesting potential benefits for muscle strength and reducing muscle breakdown, particularly in conjunction with exercise. However, evidence is mixed, and more research is needed to confirm these effects. JECFA and EFSA have evaluated related compounds, but specific evaluations for calcium HMB in food may vary.

Allergen info

Calcium HMB is not derived from any of the nine FDA major allergens. It does not contain gluten.

Products containing Calcium Beta-hydroxy-beta-methylbutyrate

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JUVEN Therapeutic Nutrition Powder Amino Acid Supplements 327kcal 9.1Protein —Fat 30.6Carbs Unflavored Therapeutic Nutrition Powder JUVEN Unflavored Therapeutic Nutrition Powder Energy, Protein & Muscle Recovery Drinks 348kcal 10.9Protein —Fat 18.3Carbs Abbott Laboratories Inc Muscle Health, Milk Chocolate Energy, Protein & Muscle Recovery Drinks High in sodium — 313% DV per serving High in saturated fat — 225% DV per serving High in cholesterol — 100% DV per serving 3125kcal 188Protein 100Fat 388Carbs Abbott Laboratories Inc Therapeutic Nutrition, Strawberry Energy, Protein & Muscle Recovery Drinks High in sodium — 313% DV per serving High in saturated fat — 225% DV per serving High in cholesterol — 100% DV per serving 3125kcal 188Protein 100Fat 375Carbs Abbott Laboratories Inc Muscle Health Has Nutrivigor, Strawberry Energy, Protein & Muscle Recovery Drinks High in sodium — 313% DV per serving High in saturated fat — 225% DV per serving High in cholesterol — 100% DV per serving 3125kcal 188Protein 100Fat 375Carbs Abbott Laboratories Inc Complete Nutrition Shake+, Vanilla Energy, Protein & Muscle Recovery Drinks High in sodium — 313% DV per serving High in saturated fat — 150% DV per serving High in cholesterol — 50% DV per serving 4375kcal 162Protein 138Fat 638Carbs Abbott Laboratories Inc Advanced Nutrition Shake, Vanilla Energy, Protein & Muscle Recovery Drinks High in sodium — 313% DV per serving High in saturated fat — 225% DV per serving High in cholesterol — 100% DV per serving 4375kcal 250Protein 138Fat 550Carbs Abbott Laboratories Inc Nutrition Shake+, Strawberry Energy, Protein & Muscle Recovery Drinks High in sodium — 313% DV per serving High in saturated fat — 150% DV per serving High in cholesterol — 50% DV per serving 4375kcal 162Protein 138Fat 638Carbs Advanced Therapeutic Nutrition For Muscle Health, Milk Chocolate Abbott Laboratories Inc Advanced Therapeutic Nutrition For Muscle Health, Milk Chocolate Energy, Protein & Muscle Recovery Drinks High in sodium — 313% DV per serving High in saturated fat — 225% DV per serving High in cholesterol — 100% DV per serving 4375kcal 250Protein 138Fat 562Carbs Abbott Laboratories Inc Vanilla Flavor Nutrition Shake, Vanilla Energy, Protein & Muscle Recovery Drinks High in sodium — 313% DV per serving High in saturated fat — 225% DV per serving High in cholesterol — 100% DV per serving 3125kcal 188Protein 100Fat 375Carbs Therapeutic Nutrition Powder Abbott Laboratories Inc Therapeutic Nutrition Powder Energy, Protein & Muscle Recovery Drinks 348kcal 10.9Protein —Fat 18.3Carbs Abbott Laboratories Inc Butter Coffee Shakes, Butter Coffee Energy, Protein & Muscle Recovery Drinks High in saturated fat — 55% DV per serving 62kcal 3.1Protein 5.2Fat 0.9Carbs
Milk Protein Concentrate (21 products) Ascorbic Acid (20 products) Natural And Artificial Flavor (20 products) Sugar (19 products) Zinc Sulfate (19 products) Soy Lecithin (18 products) Water (17 products) Dl-alpha-tocopheryl Acetate (17 products) Corn Oil (17 products) Soy Protein Isolate (17 products)

Last updated: September 28, 2026

Note: This site presents label data from USDA FoodData Central for general information. It is not medical advice. Check the package label; formulations change.