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Cobalamin, commonly known as Vitamin B12, is a water-soluble vitamin. It is naturally found in animal products and is also added to some foods. It plays a vital role in nerve function, red blood cell formation, and DNA synthesis.

Vitamin B12 is often added to foods to help people meet their daily intake needs, especially those who consume limited animal products. It is commonly found in fortified cereals, plant-based milk alternatives, and nutritional yeast.

Vitamin B12 is recognized as safe and effective by the FDA for its intended use in food fortification. The National Academies of Sciences, Engineering, and Medicine have established upper intake levels for vitamin B12. JECFA and EFSA have also evaluated vitamin B12. Low levels of B12 are common in older adults and those following vegan diets, and can lead to neurological issues or anemia.