Ingredient · E631, E627

Disodium Inosinate & Disodium Guanylate

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Source
Not animal-derived
Allergen
No
Role in food
These compounds are added to foods to boost and round out savory flavors, making …

What it is

Disodium inosinate and disodium guanylate are flavor enhancers that work together to create an umami taste, often described as savory or meaty. They are typically produced through fermentation of plant-based materials, such as sugar or molasses, using specific microorganisms.

Why it's used

These compounds are added to foods to boost and round out savory flavors, making them taste richer and more satisfying. They are commonly found in processed meats, instant noodles, snack foods like chips and crackers, and canned vegetables.

Health notes

Disodium inosinate and disodium guanylate are generally recognized as safe (GRAS) by the FDA when used as flavor enhancers. International bodies like JECFA have evaluated them and established acceptable daily intakes. While generally considered safe, some individuals may experience mild reactions like headaches or flushing, particularly with high consumption, though scientific evidence for these reactions is mixed.

Allergen info

Not a major allergen. Disodium inosinate and disodium guanylate are not derived from any of the nine major allergens recognized by the FDA, nor do they contain gluten.

Products containing Disodium Inosinate & Disodium Guanylate

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DAVID Dill Pickle Sunflower Seeds Conagra Brands DAVID Dill Pickle Sunflower Seeds Nuts/Seeds - Prepared/Processed (Shelf Stable) 633kcal 26.7Protein 53.3Fat 16.7Carbs Conagra Brands DAVID SEED Jumbo Ranch Nuts/Seeds - Prepared/Processed (Shelf Stable) 627kcal 27.4Protein 51.0Fat 15.7Carbs Conagra Brands DAVID Ranch Pumpkin Seeds Nuts/Seeds - Prepared/Processed (Shelf Stable) High in sodium — 56% DV per serving High in saturated fat — 22% DV per serving 622kcal 35.6Protein 48.9Fat 11.1Carbs ASSI BRAND Assi Brand, Fully Cooked Vegetable & Beef Dumpling Frozen Appetizers & Hors D'oeuvres 179kcal 7.1Protein 6.0Fat 23.8Carbs GOLDEN DELIGHT Potstickers Vegetable Frozen Appetizers & Hors D'oeuvres 152kcal 5.4Protein 1.1Fat 29.4Carbs GREAT AMERICAN Beef Meatballs With Barbecue Sauce Bacon, Sausages & Ribs High in sodium — 33% DV per serving High in saturated fat — 35% DV per serving High in cholesterol — 20% DV per serving 236kcal 15Protein 12.9Fat 15.7Carbs SHURFINE Baby Back Ribs Flavored Potato Chips, Baby Back Ribs Chips, Pretzels & Snacks 536kcal 7.1Protein 32.1Fat 53.6Carbs SHURFINE Wavy Red Hot Flavored Potato Chips, Red Hot Chips, Pretzels & Snacks 536kcal 7.1Protein 32.1Fat 53.6Carbs CONAGRA BRANDS Sizzlin' Bacon Sunflower Seeds, Sizzlin' Bacon Popcorn, Peanuts, Seeds & Related Snacks 600kcal 22.9Protein 48.6Fat 17.1Carbs Conagra Brands BERTOLLI Farfalle Carbonara, 10 OZ Dough Based Products / Meals High in sodium — 51% DV per serving High in saturated fat — 60% DV per serving High in cholesterol — 25% DV per serving 155kcal 9.2Protein 7.4Fat 12.4Carbs Conagra Brands MARIE CALLENDERS Savory Beef Family Recipes, 9.98 OZ Herbs/Spices/Extracts High in sodium — 23% DV per serving 370kcal 13.0Protein 3.3Fat 69.6Carbs Conagra Brands SLIM JIM Buffalo Style Wing Seasoned, 0.97 OZ Meat/Poultry/Other Animals Prepared/Processed High in sodium — 21% DV per serving High in saturated fat — 20% DV per serving 500kcal 21.4Protein 39.3Fat 14.3Carbs

Last updated: September 28, 2026

Note: This site presents label data from USDA FoodData Central for general information. It is not medical advice. Check the package label; formulations change.