Ingredient · E385

Calcium Disodium EDTA Preservative

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Source
Not animal-derived
Allergen
No
Role in food
Manufacturers add Calcium Disodium EDTA to foods to preserve freshness and prevent discoloration. It …

What it is

Calcium Disodium EDTA is a synthetic compound used as a preservative. It is made by reacting ethylenediamine with sodium chloroacetate, and then neutralizing it with calcium hydroxide. It helps to prevent spoilage by binding to metal ions that can cause oxidation.

Why it's used

Manufacturers add Calcium Disodium EDTA to foods to preserve freshness and prevent discoloration. It is often found in baked goods like cakes, cookies, and pastries, as well as in dressings, sauces, and canned goods. Its ability to chelate (bind) metal ions prevents them from catalyzing oxidation reactions that degrade flavor and color.

Health notes

Calcium Disodium EDTA is generally recognized as safe (GRAS) by the FDA for use as a food additive. It is also approved for use in other countries. Studies have shown that it is poorly absorbed by the body and is excreted unchanged. International bodies like JECFA and EFSA have evaluated its safety. While generally considered safe at typical consumption levels, some research has explored its potential effects on mineral absorption, though evidence at normal intake levels is mixed.

Allergen info

Calcium Disodium EDTA is not derived from any of the nine FDA major allergens. It does not contain gluten.

Products containing Calcium Disodium EDTA Preservative

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MARKET PANTRY Mini Frosted Sugar Cookies, Mini Frosted Cookies & Biscuits High in added sugars — 24% DV per serving 433kcal 3.3Protein 13.3Fat 70Carbs RDK Corp. Pecan Kringle Cakes, Cupcakes, Snack Cakes High in saturated fat — 22% DV per serving 404kcal 3.9Protein 23.1Fat 48.1Carbs RDK Corp. Kringle, Raspberry Croissants, Sweet Rolls, Muffins & Other Pastries 308kcal 3.9Protein 13.5Fat 46.1Carbs Mary Ann's Baking Company Mary Ann's Baking Company, Coffee Cake, Danish Pastry, Cheese, Cheese Cakes, Cupcakes, Snack Cakes 320kcal 4Protein 12Fat 48Carbs Phil's Cake Box Bakeries, Inc. Alessi Bakeries, Red Velvet Cupcakes Cakes, Cupcakes, Snack Cakes 300kcal 5Protein 12.5Fat 45Carbs RDK Corp. Almond Kringle Croissants, Sweet Rolls, Muffins & Other Pastries High in saturated fat — 22% DV per serving 380kcal 4Protein 22Fat 44Carbs RDK Corp. Kringle, Pecan Cakes, Cupcakes, Snack Cakes High in saturated fat — 20% DV per serving 400kcal 4Protein 22Fat 48Carbs Racine Danish Kringles, Kringle, Raspberry, Raspberry RDK Corp. Racine Danish Kringles, Kringle, Raspberry, Raspberry Cakes, Cupcakes, Snack Cakes 300kcal 4Protein 14Fat 44Carbs RDK Corp. Kringle, Raspberry-Cheese Cakes, Cupcakes, Snack Cakes 308kcal 3.9Protein 13.5Fat 44.2Carbs RDK Corp. Racine Danish Kringles, Turtle Danish Cakes, Cupcakes, Snack Cakes High in saturated fat — 22% DV per serving 404kcal 3.9Protein 25Fat 44.2Carbs RDK Corp. Kringles, Cinnamon Cakes, Cupcakes, Snack Cakes High in saturated fat — 22% DV per serving 380kcal 4Protein 18Fat 50Carbs RDK Corp. Danish, Merry Berry Cakes, Cupcakes, Snack Cakes High in sodium — 20% DV per serving 320kcal 4Protein 16Fat 44Carbs

Last updated: September 28, 2026

Note: This site presents label data from USDA FoodData Central for general information. It is not medical advice. Check the package label; formulations change.